Better Pumps with L-Carnitine
Researchers investigated the effect of acute L-carnitine supplementation at two different doses on nitric oxide (NO) production and oxidative stress after exhaustive exercise. The subjects were 26 healthy males aged 17-19 years. Subjects were randomly divided into two groups of 13 each and received 3 or 4 g L-carnitine via a glass of fruit juice. After 1 h, the treadmill test was started at a speed of 8 km/h, afterwards increasing the speed 1 km/h every 3 min with a 1 min rest before every speed increase until exhaustion. Venous blood samples were collected again within 5 min following the exercise test. One week later, the test was repeated on the same athletes with placebo fluids. All subjects received a placebo via a glass of fruit juice. 1 h after the same exercise protocol mentioned above was performed and blood samples were drawn immediately. These plasma samples were used for measurement of nitrate-nitrite, which are known to be the stable end products of NO, TBARs as a lipid peroxidation indicator (lipid peroxidation which is used as an indicator of oxidative damage to cells and tissues,) and an antioxidant glutathione (GSH) levels. At the end of the study, the group that received L-carnitine applied at a 3 g dose provides strong antioxidant action by increasing the antioxidant glutathione levels and NO levels and decreased the lipid peroxidation levels (damage to cells). L- Carnitine not only can increase exercise performance but it may also result in better pumps in the gym.
Atalay Guzel N, Erikoglu Orer G, Sezen Bircan F, Coskun Cevher S. Effects of acute L-carnitine supplementation on nitric oxide production and oxidative stress after exhaustive exercise in young soccer players. J Sports Med Phys Fitness. 2015 Jan-Feb;55(1-2):9-15